PDB 6eg3

PDB Information

PDB6EG3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli O157:H7
Primary Citation
Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
Papillon, J.P.N., Nakajima, K., Adair, C.D., Hempel, J., Jouk, A.O., Karki, R.G., Mathieu, S., Mobitz, H., Ntaganda, R., Smith, T., Visser, M., Hill, S.E., Hurtado, F.K., Chenail, G., Bhang, H.C., Bric, A., Xiang, K., Bushold, G., Gilbert, T., Vattay, A., Dooley, J., Costa, E.A., Park, I., Li, A., Farley, D., Lounkine, E., Yue, Q.K., Xie, X., Zhu, X., Kulathila, R., King, D., Hu, T., Vulic, K., Cantwell, J., Luu, C., Jagani, Z.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-08-17
Resolution2.840
CATH Insert Date16 Dec, 2018

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51531 SMCA2_HUMAN Homo sapiens Probable global transcription activator SNF2L2
P0AEY0 MALE_ECO57 Escherichia coli O157:H7 Maltose/maltodextrin-binding periplasmic protein