PDB 6ed6

PDB Information

PDB6ED6
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
Hobson, A.D., Judge, R.A., Aguirre, A.L., Brown, B.S., Cui, Y., Ding, P., Dominguez, E., DiGiammarino, E., Egan, D.A., Freiberg, G.M., Gopalakrishnan, S.M., Harris, C.M., Honore, M.P., Kage, K.L., Kapecki, N.J., Ling, C., Ma, J., Mack, H., Mamo, M., Maurus, S., McRae, B., Moore, N.S., Mueller, B.K., Mueller, R., Namovic, M.T., Patel, K., Pratt, S.D., Putman, C.B., Queeney, K.L., Sarris, K.K., Schaffter, L.M., Stoll, V.S., Vasudevan, A., Wang, L., Wang, L., Wirthl, W., Yach, K.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2018-08-08
Resolution2.860
CATH Insert Date16 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Holding pen
B 16 Dec, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2