PDB Information

PDB6E23
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Aho, E.R., Wang, J., Gogliotti, R.D., Howard, G.C., Phan, J., Acharya, P., Macdonald, J.D., Cheng, K., Lorey, S.L., Lu, B., Wenzel, S., Foshage, A.M., Alvarado, J., Wang, F., Shaw, J.G., Zhao, B., Weissmiller, A.M., Thomas, L.R., Vakoc, C.R., Hall, M.D., Hiebert, S.W., Liu, Q., Stauffer, S.R., Fesik, S.W., Tansey, W.P.
Cell Rep
HeaderGene Regulation/Inhibitor
Released2018-07-10
Resolution1.660
CATH Insert Date17 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6e23A00 18 Mar, 2019 2.130.10.10 Assigned
6e23B00 18 Mar, 2019 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5