PDB 6e0r

PDB Information

PDB6E0R
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors.
Fushimi, M., Fujimori, I., Wakabayashi, T., Hasui, T., Kawakita, Y., Imamura, K., Kato, T., Murakami, M., Ishii, T., Kikko, Y., Kasahara, M., Nakatani, A., Hiura, Y., Miyamoto, M., Saikatendu, K., Zou, H., Lane, S.W., Lawson, J.D., Imoto, H.
J.Med.Chem.
HeaderProtein Binding
Released2018-07-06
Resolution2.300
CATH Insert Date05 May, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6e0rA01 06 May, 2019 3.30.200.20 Assigned
6e0rA02 06 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor