PDB 6dna

PDB Information

PDB6DNA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Holt, M.C., Assar, Z., Beheshti Zavareh, R., Lin, L., Anglin, J., Mashadova, O., Haldar, D., Mullarky, E., Kremer, D.M., Cantley, L.C., Kimmelman, A.C., Stein, A.J., Lairson, L.L., Lyssiotis, C.A.
Biochemistry
HeaderTransferase
Released2018-06-06
Resolution3.000
CATH Insert Date16 Dec, 2018

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped
E 16 Dec, 2018 Chopped
F 16 Dec, 2018 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6dnaA01 28 Feb, 2019 Holding pen
6dnaA02 28 Feb, 2019 3.40.640.10 Assigned
6dnaB01 28 Feb, 2019 Holding pen
6dnaB02 28 Feb, 2019 3.40.640.10 Assigned
6dnaC01 28 Feb, 2019 Holding pen
6dnaC02 28 Feb, 2019 3.40.640.10 Assigned
6dnaD01 28 Feb, 2019 Holding pen
6dnaD02 28 Feb, 2019 3.40.640.10 Assigned
6dnaE01 28 Feb, 2019 Holding pen
6dnaE02 28 Feb, 2019 3.40.640.10 Assigned
6dnaF01 28 Feb, 2019 Holding pen
6dnaF02 28 Feb, 2019 3.40.640.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic
P17174 AATC_HUMAN Homo sapiens Aspartate aminotransferase, cytoplasmic