PDB 6di9

PDB Information

PDB6DI9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.
Qiu, H., Liu-Bujalski, L., Caldwell, R.D., Follis, A.V., Gardberg, A., Goutopoulos, A., Grenningloh, R., Head, J., Johnson, T., Jones, R., Mochalkin, I., Morandi, F., Neagu, C., Sherer, B.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2018-05-23
Resolution1.250
CATH Insert Date09 Sep, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Sep, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6di9A01 10 Sep, 2018 3.30.200.20 Assigned
6di9A02 10 Sep, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
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