PDB 6das

PDB Information

PDB6DAS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.
Wang, F., Jeon, K.O., Salovich, J.M., Macdonald, J.D., Alvarado, J., Gogliotti, R.D., Phan, J., Olejniczak, E.T., Sun, Q., Wang, S., Camper, D., Yuh, J.P., Shaw, J.G., Sai, J., Rossanese, O.W., Tansey, W.P., Stauffer, S.R., Fesik, S.W.
J. Med. Chem.
HeaderDna Binding Protein/Inhibitor
Released2018-05-01
Resolution1.800
CATH Insert Date22 Jul, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Jul, 2018 Chopped
B 22 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6dasA00 23 Jul, 2018 2.130.10.10 Assigned
6dasB00 23 Jul, 2018 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5