PDB 6cur

PDB Links
Overview

PDB Information

PDB	6CUR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. Abbott, J.R., Patel, P.A., Howes, J.E., Akan, D.T., Kennedy, J.P., Burns, M.C., Browning, C.F., Sun, Q., Rossanese, O.W., Phan, J., Waterson, A.G., Fesik, S.W. ACS Med Chem Lett
Header	Signaling Protein
Released	2018-03-26
Resolution	1.730
CATH Insert Date	10 Feb, 2019

PDB Images (8)

Image of CATH 6cur

6cur

PDB 6cur

Image of CATH 6curA

6curA

PDB Chain 6curA

Image of CATH 6curB

6curB

PDB Chain 6curB

Image of CATH 6curC

6curC

PDB Chain 6curC

Image of CATH 6curA00

6curA00

CATH Domain 6curA00

Image of CATH 6curB01

6curB01

CATH Domain 6curB01

Image of CATH 6curB02

6curB02

CATH Domain 6curB02

Image of CATH 6curC00

6curC00

CATH Domain 6curC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	10 Feb, 2019	Chopped
B	10 Feb, 2019	Chopped
C	10 Feb, 2019	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6curA00	11 Feb, 2019	3.40.50.300	Assigned
6curB01	11 Feb, 2019	1.20.870.10	Assigned
6curB02	11 Feb, 2019	1.10.840.10	Assigned
6curC00	11 Feb, 2019	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas