PDB 6ckr

PDB Information

PDB6CKR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.
Bennett, M.J., Wu, Y., Boloor, A., Matuszkiewicz, J., O'Connell, S.M., Shi, L., Stansfield, R.K., Del Rosario, J.R., Veal, J.M., Hosfield, D.J., Xu, J., Kaldor, S.W., Stafford, J.A., Betancort, J.M.
Bioorg. Med. Chem. Lett.
HeaderGene Regulation/Inhibitor
Released2018-02-28
Resolution1.620
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ckrA01 29 Jun, 2018 1.20.920.10 Assigned
6ckrB01 29 Jun, 2018 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4