PDB 6cir

PDB Links
Overview

PDB Information

PDB	6CIR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2. Fehl, C., Vogt, C.D., Yadav, R., Li, K., Scott, E.E., Aube, J. J. Med. Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2018-02-25
Resolution	2.650
CATH Insert Date	06 Jul, 2018

PDB Images (9)

Image of CATH 6cir

6cir

PDB 6cir

Image of CATH 6cirA

6cirA

PDB Chain 6cirA

Image of CATH 6cirB

6cirB

PDB Chain 6cirB

Image of CATH 6cirC

6cirC

PDB Chain 6cirC

Image of CATH 6cirD

6cirD

PDB Chain 6cirD

Image of CATH 6cirA00

6cirA00

CATH Domain 6cirA00

Image of CATH 6cirB00

6cirB00

CATH Domain 6cirB00

Image of CATH 6cirC00

6cirC00

CATH Domain 6cirC00

Image of CATH 6cirD00

6cirD00

CATH Domain 6cirD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jul, 2018	Chopped
B	06 Jul, 2018	Chopped
C	06 Jul, 2018	Chopped
D	06 Jul, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6cirA00	19 Jul, 2018	1.10.630.10	Assigned
6cirB00	19 Jul, 2018	1.10.630.10	Assigned
6cirC00	19 Jul, 2018	1.10.630.10	Assigned
6cirD00	19 Jul, 2018	1.10.630.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P05093	CP17A_HUMAN	Homo sapiens	Steroid 17-alpha-hydroxylase/17,20 lyase
P05093	CP17A_HUMAN	Homo sapiens	Steroid 17-alpha-hydroxylase/17,20 lyase
P05093	CP17A_HUMAN	Homo sapiens	Steroid 17-alpha-hydroxylase/17,20 lyase
P05093	CP17A_HUMAN	Homo sapiens	Steroid 17-alpha-hydroxylase/17,20 lyase