PDB 6c2i

PDB Information

PDB6C2I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Diastereoselective synthesis of fused cyclopropyl-3-amino-2,4-oxazine beta-amyloid cleaving enzyme (BACE) inhibitors and their biological evaluation.
Low, J.D., Bartberger, M.D., Cheng, Y., Whittington, D., Xue, Q., Wood, S., Allen, J.R., Minatti, A.E.
Bioorg. Med. Chem. Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-01-08
Resolution1.950
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6c2iA01 28 Jun, 2018 2.40.70.10 Assigned
6c2iA02 28 Jun, 2018 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1