PDB 6bry

PDB Information

PDB6BRY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
Banerjee, S., Arnst, K.E., Wang, Y., Kumar, G., Deng, S., Yang, L., Li, G.B., Yang, J., White, S.W., Li, W., Miller, D.D.
J. Med. Chem.
HeaderCell Cycle
Released2017-12-01
Resolution2.700
CATH Insert Date06 Jul, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Chopped
D 06 Jul, 2018 Chopped
E 06 Jul, 2018 Chopped
F 06 Jul, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6bryA01 19 Jul, 2018 3.40.50.1440 Assigned
6bryA02 19 Jul, 2018 3.30.1330.20 Assigned
6bryA03 19 Jul, 2018 1.10.287.600 Assigned
6bryB01 19 Jul, 2018 3.40.50.1440 Assigned
6bryB02 19 Jul, 2018 3.30.1330.20 Assigned
6bryB03 19 Jul, 2018 1.10.287.600 Assigned
6bryC01 19 Jul, 2018 3.40.50.1440 Assigned
6bryC02 19 Jul, 2018 3.30.1330.20 Assigned
6bryC03 19 Jul, 2018 1.10.287.600 Assigned
6bryD01 19 Jul, 2018 3.40.50.1440 Assigned
6bryD02 19 Jul, 2018 3.30.1330.20 Assigned
6bryD03 19 Jul, 2018 1.10.287.600 Assigned
6bryE01 19 Jul, 2018 6.10.280.30 Assigned
6bryF01 19 Jul, 2018 3.40.50.11480 Assigned
6bryF02 19 Jul, 2018 3.30.470.20 Assigned
6bryF03 19 Jul, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
P02554 TBB_PIG Sus scrofa Tubulin beta chain
Q9H169 STMN4_HUMAN Homo sapiens Stathmin-4
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P02554 TBB_PIG Sus scrofa Tubulin beta chain
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