PDB 6bag

PDB Information

PDB6BAG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase
Wei, B., Labadie, S.S., Robarge, K., Chen, J., Chen, Z., Corson, L.B., Ding, C.Z., DiPasquale, A.G., Dragovich, P.S., Eigenbrot, C., Evangelista, M., Fauber, B.P., Goa, Z., Ge, H., Hitz, A., Ho, Q., Lai, K.W., Liu, W., Liu, Y., Li, C., Ma, S., Malek, S., O'Brien, T., Pang, J., Peterson, D., Salphati, L., Sideris, S., Ultsch, M., Yen, I., Yue, Q., Zhang, H., Zhou, A., Purkey, H.E.
To Be Published
HeaderOxidoreductase/Inhibitor
Released2017-10-12
Resolution2.400
CATH Insert Date16 Dec, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6bagA01 28 Feb, 2019 3.40.50.720 Assigned
6bagA02 28 Feb, 2019 3.90.110.10 Assigned
6bagB01 28 Feb, 2019 3.40.50.720 Assigned
6bagB02 28 Feb, 2019 3.90.110.10 Assigned
6bagC01 28 Feb, 2019 3.40.50.720 Assigned
6bagC02 28 Feb, 2019 3.90.110.10 Assigned
6bagD01 27 Feb, 2019 3.40.50.720 Assigned
6bagD02 27 Feb, 2019 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
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