PDB Information

PDB6B96
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design.
Forster, A.B., Abeywickrema, P., Bunda, J., Cox, C.D., Cabalu, T.D., Egbertson, M., Fay, J., Getty, K., Hall, D., Kornienko, M., Lu, J., Parthasarathy, G., Reid, J., Sharma, S., Shipe, W.D., Smith, S.M., Soisson, S., Stachel, S.J., Su, H.P., Wang, D., Berger, R.
Bioorg. Med. Chem. Lett.
HeaderHydrolase
Released2017-10-10
Resolution1.880
CATH Insert Date17 Dec, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6b96A00 24 Dec, 2017 1.10.1300.10 Assigned
6b96B00 24 Dec, 2017 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase