PDB 6b8o

PDB Information

PDB6B8O
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
Sudom, A., Talreja, S., Danao, J., Bragg, E., Kegel, R., Min, X., Richardson, J., Zhang, Z., Sharkov, N., Marcora, E., Thibault, S., Bradley, J., Wood, S., Lim, A.C., Chen, H., Wang, S., Foltz, I.N., Sambashivan, S., Wang, Z.
J. Biol. Chem.
HeaderSignaling Protein
Released2017-10-09
Resolution2.200
CATH Insert Date06 Jul, 2018

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Chopped
D 06 Jul, 2018 Chopped
E 06 Jul, 2018 Chopped
F 06 Jul, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6b8oA00 19 Jul, 2018 2.60.40.10 Assigned
6b8oB00 19 Jul, 2018 2.60.40.10 Assigned
6b8oC00 19 Jul, 2018 2.60.40.10 Assigned
6b8oD00 19 Jul, 2018 2.60.40.10 Assigned
6b8oE00 19 Jul, 2018 2.60.40.10 Assigned
6b8oF00 19 Jul, 2018 2.60.40.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2