PDB 6b4u

PDB Information

PDB6B4U
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Bruncko, M., Wang, L., Sheppard, G.S., Phillips, D.C., Tahir, S.K., Xue, J., Erickson, S., Fidanze, S., Fry, E., Hasvold, L., Jenkins, G.J., Jin, S., Judge, R.A., Kovar, P.J., Madar, D., Nimmer, P., Park, C., Petros, A.M., Rosenberg, S.H., Smith, M.L., Song, X., Sun, C., Tao, Z.F., Wang, X., Xiao, Y., Zhang, H., Tse, C., Leverson, J.D., Elmore, S.W., Souers, A.J.
J. Med. Chem.
HeaderSignaling Protein/Inhibitor
Released2017-09-27
Resolution1.950
CATH Insert Date14 Nov, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6b4uA01 10 Dec, 2017 1.10.437.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
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