PDB 6arj

PDB Information

PDB6ARJ
MethodX-RAY DIFFRACTION
Host OrganismInsect cell expression vector pTIE1
Gene SourceHomo sapiens
Primary Citation
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma.
Drew, A.E., Moradei, O., Jacques, S.L., Rioux, N., Boriack-Sjodin, A.P., Allain, C., Scott, M.P., Jin, L., Raimondi, A., Handler, J.L., Ott, H.M., Kruger, R.G., McCabe, M.T., Sneeringer, C., Riera, T., Shapiro, G., Waters, N.J., Mitchell, L.H., Duncan, K.W., Moyer, M.P., Copeland, R.A., Smith, J., Chesworth, R., Ribich, S.A.
Sci Rep
HeaderTransferase
Released2017-08-22
Resolution1.920
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6arjA01 28 Jun, 2018 3.40.50.150 Assigned
6arjA02 28 Jun, 2018 2.70.160.11 Assigned
6arjB01 28 Jun, 2018 3.40.50.150 Assigned
6arjB02 28 Jun, 2018 2.70.160.11 Assigned
6arjC01 28 Jun, 2018 3.40.50.150 Assigned
6arjC02 28 Jun, 2018 2.70.160.11 Assigned
6arjD01 28 Jun, 2018 3.40.50.150 Assigned
6arjD02 28 Jun, 2018 2.70.160.11 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1
Q86X55 CARM1_HUMAN Homo sapiens Histone-arginine methyltransferase CARM1