PDB 5xs2

PDB Links
Overview

PDB Information

PDB	5XS2
Method	X-RAY DIFFRACTION
Host Organism	unidentified baculovirus
Gene Source	Homo sapiens
Primary Citation	Discovery of potent and selective CDK8 inhibitors through FBDD approach Han, X., Jiang, M., Zhou, C., Zhou, Z., Xu, Z., Wang, L., Mayweg, A.V., Niu, R., Jin, T.G., Yang, S. Bioorg. Med. Chem. Lett.
Header	Transferase
Released	2017-06-12
Resolution	2.040
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5xs2

5xs2

PDB 5xs2

Image of CATH 5xs2A

5xs2A

PDB Chain 5xs2A

Image of CATH 5xs2B

5xs2B

PDB Chain 5xs2B

Image of CATH 5xs2A01

5xs2A01

CATH Domain 5xs2A01

Image of CATH 5xs2A02

5xs2A02

CATH Domain 5xs2A02

Image of CATH 5xs2B01

5xs2B01

CATH Domain 5xs2B01

Image of CATH 5xs2B02

5xs2B02

CATH Domain 5xs2B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5xs2A01	10 Dec, 2017	3.30.200.20	Assigned
5xs2A02	10 Dec, 2017	1.10.510.10	Assigned
5xs2B01	10 Dec, 2017	1.10.472.10	Assigned
5xs2B02	10 Dec, 2017	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C