PDB 5xag

PDB Information

PDB5XAG
MethodX-RAY DIFFRACTION
Host OrganismBos taurus
Gene SourceBos taurus
Primary Citation
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Zhou, P., Liang, Y., Zhang, H., Jiang, H., Feng, K., Xu, P., Wang, J., Wang, X., Ding, K., Luo, C., Liu, M., Wang, Y.
Eur J Med Chem
HeaderStructural Protein
Released2017-03-12
Resolution2.560
CATH Insert Date03 Jun, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped
E 03 Jun, 2018 Chopped
F 03 Jun, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5xagA01 28 Jun, 2018 3.40.50.1440 Assigned
5xagA02 28 Jun, 2018 3.30.1330.20 Assigned
5xagA03 28 Jun, 2018 1.10.287.600 Assigned
5xagB01 28 Jun, 2018 3.40.50.1440 Assigned
5xagB02 28 Jun, 2018 3.30.1330.20 Assigned
5xagB03 28 Jun, 2018 1.10.287.600 Assigned
5xagC01 28 Jun, 2018 3.40.50.1440 Assigned
5xagC02 28 Jun, 2018 3.30.1330.20 Assigned
5xagC03 28 Jun, 2018 1.10.287.600 Assigned
5xagD01 28 Jun, 2018 3.40.50.1440 Assigned
5xagD02 28 Jun, 2018 3.30.1330.20 Assigned
5xagD03 28 Jun, 2018 1.10.287.600 Assigned
5xagE01 28 Jun, 2018 6.10.280.30 Assigned
5xagF01 28 Jun, 2018 3.40.50.11480 Assigned
5xagF02 28 Jun, 2018 3.30.470.20 Assigned
5xagF03 28 Jun, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain