PDB 5xaf

PDB Information

PDB5XAF
MethodX-RAY DIFFRACTION
Host OrganismBos taurus
Gene SourceBos taurus
Primary Citation
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Zhou, P., Liang, Y., Zhang, H., Jiang, H., Feng, K., Xu, P., Wang, J., Wang, X., Ding, K., Luo, C., Liu, M., Wang, Y.
Eur J Med Chem
HeaderStructural Protein
Released2017-03-12
Resolution2.550
CATH Insert Date07 Jan, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped
E 07 Jan, 2018 Chopped
F 07 Jan, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5xafA01 11 Jan, 2018 3.40.50.1440 Assigned
5xafA02 11 Jan, 2018 3.30.1330.20 Assigned
5xafA03 11 Jan, 2018 1.10.287.600 Assigned
5xafB01 11 Jan, 2018 3.40.50.1440 Assigned
5xafB02 11 Jan, 2018 3.30.1330.20 Assigned
5xafB03 11 Jan, 2018 1.10.287.600 Assigned
5xafC01 11 Jan, 2018 3.40.50.1440 Assigned
5xafC02 11 Jan, 2018 3.30.1330.20 Assigned
5xafC03 11 Jan, 2018 1.10.287.600 Assigned
5xafD01 11 Jan, 2018 3.40.50.1440 Assigned
5xafD02 11 Jan, 2018 3.30.1330.20 Assigned
5xafD03 11 Jan, 2018 1.10.287.600 Assigned
5xafE01 11 Jan, 2018 6.10.280.30 Assigned
5xafF01 11 Jan, 2018 3.40.50.11480 Assigned
5xafF02 11 Jan, 2018 3.30.470.20 Assigned
5xafF03 11 Jan, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain