PDB 5xaf
PDB Information
| PDB | 5XAF |
| Method | X-RAY DIFFRACTION |
| Host Organism | Bos taurus |
| Gene Source | Bos taurus |
| Primary Citation | Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Eur J Med Chem
|
| Header | Structural Protein |
| Released | 2017-03-12 |
| Resolution | 2.550 |
| CATH Insert Date | 07 Jan, 2018 |
PDB Images (23)
5xaf
PDB 5xaf
5xafA
PDB Chain 5xafA
5xafB
PDB Chain 5xafB
5xafC
PDB Chain 5xafC
5xafD
PDB Chain 5xafD
5xafE
PDB Chain 5xafE
5xafF
PDB Chain 5xafF
5xafA01
CATH Domain 5xafA01
5xafA02
CATH Domain 5xafA02
5xafA03
CATH Domain 5xafA03
5xafB01
CATH Domain 5xafB01
5xafB02
CATH Domain 5xafB02
5xafB03
CATH Domain 5xafB03
5xafC01
CATH Domain 5xafC01
5xafC02
CATH Domain 5xafC02
5xafC03
CATH Domain 5xafC03
5xafD01
CATH Domain 5xafD01
5xafD02
CATH Domain 5xafD02
5xafD03
CATH Domain 5xafD03
5xafE01
CATH Domain 5xafE01
5xafF01
CATH Domain 5xafF01
5xafF02
CATH Domain 5xafF02
5xafF03
CATH Domain 5xafF03
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 07 Jan, 2018 | Chopped |
| B | 07 Jan, 2018 | Chopped |
| C | 07 Jan, 2018 | Chopped |
| D | 07 Jan, 2018 | Chopped |
| E | 07 Jan, 2018 | Chopped |
| F | 07 Jan, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5xafA01 | 11 Jan, 2018 | 3.40.50.1440 | Assigned |
| 5xafA02 | 11 Jan, 2018 | 3.30.1330.20 | Assigned |
| 5xafA03 | 11 Jan, 2018 | 1.10.287.600 | Assigned |
| 5xafB01 | 11 Jan, 2018 | 3.40.50.1440 | Assigned |
| 5xafB02 | 11 Jan, 2018 | 3.30.1330.20 | Assigned |
| 5xafB03 | 11 Jan, 2018 | 1.10.287.600 | Assigned |
| 5xafC01 | 11 Jan, 2018 | 3.40.50.1440 | Assigned |
| 5xafC02 | 11 Jan, 2018 | 3.30.1330.20 | Assigned |
| 5xafC03 | 11 Jan, 2018 | 1.10.287.600 | Assigned |
| 5xafD01 | 11 Jan, 2018 | 3.40.50.1440 | Assigned |
| 5xafD02 | 11 Jan, 2018 | 3.30.1330.20 | Assigned |
| 5xafD03 | 11 Jan, 2018 | 1.10.287.600 | Assigned |
| 5xafE01 | 11 Jan, 2018 | 6.10.280.30 | Assigned |
| 5xafF01 | 11 Jan, 2018 | 3.40.50.11480 | Assigned |
| 5xafF02 | 11 Jan, 2018 | 3.30.470.20 | Assigned |
| 5xafF03 | 11 Jan, 2018 | 3.30.1490.20 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P81947 | TBA1B_BOVIN | Bos taurus | Tubulin alpha-1B chain |
| P63043 | STMN4_RAT | Rattus norvegicus | Stathmin-4 |
| Q6B856 | TBB2B_BOVIN | Bos taurus | Tubulin beta-2B chain |
| Q6B856 | TBB2B_BOVIN | Bos taurus | Tubulin beta-2B chain |
| P81947 | TBA1B_BOVIN | Bos taurus | Tubulin alpha-1B chain |
| E1BQ43 | E1BQ43_CHICK | Gallus gallus | Uncharacterized protein |
