PDB 5x8l

PDB Links
Overview

PDB Information

PDB	5X8L
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli-Pichia pastoris shuttle vector pPpARG4
Gene Source	Homo sapiens
Primary Citation	Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Lee, H.T., Lee, J.Y., Lim, H., Lee, S.H., Moon, Y.J., Pyo, H.J., Ryu, S.E., Shin, W., Heo, Y.S. Sci Rep
Header	Immune System
Released	2017-03-03
Resolution	3.100
CATH Insert Date	14 Nov, 2017

PDB Images (41)

5x8l

PDB 5x8l

5x8lA

PDB Chain 5x8lA

5x8lB

PDB Chain 5x8lB

5x8lC

PDB Chain 5x8lC

5x8lD

PDB Chain 5x8lD

5x8lE

PDB Chain 5x8lE

5x8lF

PDB Chain 5x8lF

5x8lG

PDB Chain 5x8lG

5x8lH

PDB Chain 5x8lH

5x8lJ

PDB Chain 5x8lJ

5x8lK

PDB Chain 5x8lK

5x8lL

PDB Chain 5x8lL

5x8lM

PDB Chain 5x8lM

5x8lN

PDB Chain 5x8lN

5x8lO

PDB Chain 5x8lO

5x8lS

PDB Chain 5x8lS

5x8lA00

CATH Domain 5x8lA00

5x8lB00

CATH Domain 5x8lB00

5x8lC00

CATH Domain 5x8lC00

5x8lD00

CATH Domain 5x8lD00

5x8lE00

CATH Domain 5x8lE00

5x8lF01

CATH Domain 5x8lF01

5x8lF02

CATH Domain 5x8lF02

5x8lG01

CATH Domain 5x8lG01

5x8lG02

CATH Domain 5x8lG02

5x8lH01

CATH Domain 5x8lH01

5x8lH02

CATH Domain 5x8lH02

5x8lJ01

CATH Domain 5x8lJ01

5x8lJ02

CATH Domain 5x8lJ02

5x8lK01

CATH Domain 5x8lK01

5x8lK02

CATH Domain 5x8lK02

5x8lL01

CATH Domain 5x8lL01

5x8lL02

CATH Domain 5x8lL02

5x8lM01

CATH Domain 5x8lM01

5x8lM02

CATH Domain 5x8lM02

5x8lN01

CATH Domain 5x8lN01

5x8lN02

CATH Domain 5x8lN02

5x8lO01

CATH Domain 5x8lO01

5x8lO02

CATH Domain 5x8lO02

5x8lS01

CATH Domain 5x8lS01

5x8lS02

CATH Domain 5x8lS02

PDB Prints

PDB Chains (15)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
C	14 Nov, 2017	Chopped
D	14 Nov, 2017	Chopped
E	14 Nov, 2017	Chopped
F	14 Nov, 2017	Chopped
G	14 Nov, 2017	Chopped
H	14 Nov, 2017	Chopped
J	14 Nov, 2017	Chopped
K	14 Nov, 2017	Chopped
L	14 Nov, 2017	Chopped
M	14 Nov, 2017	Chopped
N	14 Nov, 2017	Chopped
O	14 Nov, 2017	Chopped
S	14 Nov, 2017	Chopped

CATH Domains (25)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5x8lA00	10 Dec, 2017	2.60.40.10	Assigned
5x8lB00	10 Dec, 2017	2.60.40.10	Assigned
5x8lC00	10 Dec, 2017	2.60.40.10	Assigned
5x8lD00	10 Dec, 2017	2.60.40.10	Assigned
5x8lE00	10 Dec, 2017	2.60.40.10	Assigned
5x8lF01	10 Dec, 2017		Holding pen
5x8lF02	10 Dec, 2017	2.60.40.10	Assigned
5x8lG01	10 Dec, 2017		Holding pen
5x8lG02	10 Dec, 2017	2.60.40.10	Assigned
5x8lH01	10 Dec, 2017		Holding pen
5x8lH02	10 Dec, 2017	2.60.40.10	Assigned
5x8lJ01	10 Dec, 2017		Holding pen
5x8lJ02	10 Dec, 2017	2.60.40.10	Assigned
5x8lK01	10 Dec, 2017	2.60.40.10	Assigned
5x8lK02	10 Dec, 2017	2.60.40.10	Assigned
5x8lL01	10 Dec, 2017	2.60.40.10	Assigned
5x8lL02	10 Dec, 2017	2.60.40.10	Assigned
5x8lM01	10 Dec, 2017	2.60.40.10	Assigned
5x8lM02	10 Dec, 2017	2.60.40.10	Assigned
5x8lN01	10 Dec, 2017	2.60.40.10	Assigned
5x8lN02	10 Dec, 2017	2.60.40.10	Assigned
5x8lO01	10 Dec, 2017	2.60.40.10	Assigned
5x8lO02	10 Dec, 2017	2.60.40.10	Assigned
5x8lS01	10 Dec, 2017		Holding pen
5x8lS02	10 Dec, 2017	2.60.40.10	Assigned

UniProtKB Entries (5)

Accession	Gene ID	Taxon	Description
Q9NZQ7	PD1L1_HUMAN	Homo sapiens	Programmed cell death 1 ligand 1
Q9NZQ7	PD1L1_HUMAN	Homo sapiens	Programmed cell death 1 ligand 1
Q9NZQ7	PD1L1_HUMAN	Homo sapiens	Programmed cell death 1 ligand 1
Q9NZQ7	PD1L1_HUMAN	Homo sapiens	Programmed cell death 1 ligand 1
Q9NZQ7	PD1L1_HUMAN	Homo sapiens	Programmed cell death 1 ligand 1