PDB Information

PDB5WDM
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.
Glidden, M.D., Aldabbagh, K., Phillips, N.B., Carr, K., Chen, Y.S., Whittaker, J., Phillips, M., Wickramasinghe, N.P., Rege, N., Swain, M., Peng, Y., Yang, Y., Lawrence, M.C., Yee, V.C., Ismail-Beigi, F., Weiss, M.A.
J. Biol. Chem.
HeaderHormone
Released2017-07-05
Resolution2.800
CATH Insert Date17 Dec, 2017

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped
E 17 Dec, 2017 Chopped
F 17 Dec, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5wdmA00 23 Dec, 2017 1.10.100.10 Assigned
5wdmB00 23 Dec, 2017 1.10.100.10 Assigned
5wdmC00 23 Dec, 2017 1.10.100.10 Assigned
5wdmD00 23 Dec, 2017 1.10.100.10 Assigned
5wdmE00 23 Dec, 2017 1.10.100.10 Assigned
5wdmF00 23 Dec, 2017 1.10.100.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin
P01308 INS_HUMAN Homo sapiens Insulin