PDB 5w5j

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Overview

PDB Information

PDB	5W5J
Method	X-RAY DIFFRACTION
Host Organism	unidentified baculovirus
Gene Source	Homo sapiens
Primary Citation	Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. He, X., Da Ros, S., Nelson, J., Zhu, X., Jiang, T., Okram, B., Jiang, S., Michellys, P.Y., Iskandar, M., Espinola, S., Jia, Y., Bursulaya, B., Kreusch, A., Gao, M.Y., Spraggon, G., Baaten, J., Clemmer, L., Meeusen, S., Huang, D., Hill, R., Nguyen-Tran, V., Fathman, J., Liu, B., Tuntland, T., Gordon, P., Hollenbeck, T., Ng, K., Shi, J., Bordone, L., Liu, H. ACS Med Chem Lett
Header	Hydrolase/Hydrolase Inhibitor
Released	2017-06-15
Resolution	2.850
CATH Insert Date	14 Nov, 2017

PDB Images (5)

Image of CATH 5w5j

5w5j

PDB 5w5j

Image of CATH 5w5jA

5w5jA

PDB Chain 5w5jA

Image of CATH 5w5jB

5w5jB

PDB Chain 5w5jB

Image of CATH 5w5jA00

5w5jA00

CATH Domain 5w5jA00

Image of CATH 5w5jB00

5w5jB00

CATH Domain 5w5jB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5w5jA00	16 Dec, 2017	1.10.510.10	Assigned
5w5jB00	16 Dec, 2017	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2