PDB 5vlp

PDB Links
Overview

PDB Information

PDB	5VLP
Method	X-RAY DIFFRACTION
Host Organism	Cricetulus griseus
Gene Source	Homo sapiens
Primary Citation	Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Zhang, Y., Ultsch, M., Skelton, N.J., Burdick, D.J., Beresini, M.H., Li, W., Kong-Beltran, M., Peterson, A., Quinn, J., Chiu, C., Wu, Y., Shia, S., Moran, P., Di Lello, P., Eigenbrot, C., Kirchhofer, D. Nat. Struct. Mol. Biol.
Header	Hydrolase
Released	2017-04-25
Resolution	2.900
CATH Insert Date	14 Nov, 2017

PDB Images (12)

Image of CATH 5vlp

5vlp

PDB 5vlp

Image of CATH 5vlpA

5vlpA

PDB Chain 5vlpA

Image of CATH 5vlpH

5vlpH

PDB Chain 5vlpH

Image of CATH 5vlpL

5vlpL

PDB Chain 5vlpL

Image of CATH 5vlpZ

5vlpZ

PDB Chain 5vlpZ

Image of CATH 5vlpA01

5vlpA01

CATH Domain 5vlpA01

Image of CATH 5vlpA02

5vlpA02

CATH Domain 5vlpA02

Image of CATH 5vlpA03

5vlpA03

CATH Domain 5vlpA03

Image of CATH 5vlpH01

5vlpH01

CATH Domain 5vlpH01

Image of CATH 5vlpH02

5vlpH02

CATH Domain 5vlpH02

Image of CATH 5vlpL01

5vlpL01

CATH Domain 5vlpL01

Image of CATH 5vlpL02

5vlpL02

CATH Domain 5vlpL02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
H	14 Nov, 2017	Chopped
L	14 Nov, 2017	Chopped
Z	14 Nov, 2017	Rejected

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5vlpA01	10 Apr, 2018	3.30.70.80	Assigned
5vlpA02	10 Apr, 2018	3.40.50.200	Assigned
5vlpA03	10 Apr, 2018	2.60.120.690	Assigned
5vlpH01	10 Dec, 2017		Holding pen
5vlpH02	10 Dec, 2017	2.60.40.10	Assigned
5vlpL01	10 Dec, 2017	2.60.40.10	Assigned
5vlpL02	10 Dec, 2017	2.60.40.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9