PDB 5v9t

PDB Information

PDB5V9T
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Liang, J., Labadie, S., Zhang, B., Ortwine, D.F., Patel, S., Vinogradova, M., Kiefer, J.R., Mauer, T., Gehling, V.S., Harmange, J.C., Cummings, R., Lai, T., Liao, J., Zheng, X., Liu, Y., Gustafson, A., Van der Porten, E., Mao, W., Liederer, B.M., Deshmukh, G., An, L., Ran, Y., Classon, M., Trojer, P., Dragovich, P.S., Murray, L.
Bioorg. Med. Chem. Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-03-23
Resolution3.050
CATH Insert Date14 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Holding pen
B 15 May, 2017 Domchop review
G 15 May, 2017 Rejected

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29375 KDM5A_HUMAN Homo sapiens Lysine-specific demethylase 5A
P29375 KDM5A_HUMAN Homo sapiens Lysine-specific demethylase 5A