PDB 5v9l

PDB Links
Overview

PDB Information

PDB	5V9L
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli K-12
Gene Source	Homo sapiens
Primary Citation	Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. Zeng, M., Lu, J., Li, L., Feru, F., Quan, C., Gero, T.W., Ficarro, S.B., Xiong, Y., Ambrogio, C., Paranal, R.M., Catalano, M., Shao, J., Wong, K.K., Marto, J.A., Fischer, E.S., Janne, P.A., Scott, D.A., Westover, K.D., Gray, N.S. Cell Chem Biol
Header	Hydrolase/Hydrolase Inhibitor
Released	2017-03-23
Resolution	1.980
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5v9l

5v9l

PDB 5v9l

Image of CATH 5v9lA

5v9lA

PDB Chain 5v9lA

Image of CATH 5v9lB

5v9lB

PDB Chain 5v9lB

Image of CATH 5v9lC

5v9lC

PDB Chain 5v9lC

Image of CATH 5v9lA00

5v9lA00

CATH Domain 5v9lA00

Image of CATH 5v9lB00

5v9lB00

CATH Domain 5v9lB00

Image of CATH 5v9lC00

5v9lC00

CATH Domain 5v9lC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
C	14 Nov, 2017	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5v9lA00	10 Dec, 2017	3.40.50.300	Assigned
5v9lB00	10 Dec, 2017	3.40.50.300	Assigned
5v9lC00	10 Dec, 2017	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01116	RASK_HUMAN	Homo sapiens	GTPase KRas
P01116	RASK_HUMAN	Homo sapiens	GTPase KRas
P01116	RASK_HUMAN	Homo sapiens	GTPase KRas