PDB 5utz

PDB Information

PDB5UTZ
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.
Trotta, E., Bessette, P.H., Silveria, S.L., Ely, L.K., Jude, K.M., Le, D.T., Holst, C.R., Coyle, A., Potempa, M., Lanier, L.L., Garcia, K.C., Crellin, N.K., Rondon, I.J., Bluestone, J.A.
Nat. Med.
HeaderCytokine/Immune System
Released2017-02-15
Resolution2.750
CATH Insert Date16 Jul, 2018

PDB Images (25)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Holding pen
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped
E 16 Jul, 2018 Chopped
F 16 Jul, 2018 Holding pen
G 16 Jul, 2018 Chopped
H 16 Jul, 2018 Holding pen
I 16 Jul, 2018 Chopped
J 16 Jul, 2018 Holding pen
K 16 Jul, 2018 Chopped
L 16 Jul, 2018 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5utzA00 19 Jul, 2018 1.20.1250.10 Assigned
5utzC01 19 Jul, 2018 2.60.40.10 Assigned
5utzC02 19 Jul, 2018 2.60.40.10 Assigned
5utzD00 19 Jul, 2018 1.20.1250.10 Assigned
5utzE00 19 Jul, 2018 1.20.1250.10 Assigned
5utzG01 19 Jul, 2018 2.60.40.10 Assigned
5utzG02 19 Jul, 2018 2.60.40.10 Assigned
5utzI00 19 Jul, 2018 1.20.1250.10 Assigned
5utzK01 19 Jul, 2018 2.60.40.10 Assigned
5utzK02 19 Jul, 2018 2.60.40.10 Assigned
5utzL01 19 Jul, 2018 2.60.40.10 Assigned
5utzL02 19 Jul, 2018 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P60568 IL2_HUMAN Homo sapiens Interleukin-2
P60568 IL2_HUMAN Homo sapiens Interleukin-2
P60568 IL2_HUMAN Homo sapiens Interleukin-2
P60568 IL2_HUMAN Homo sapiens Interleukin-2