PDB 5uop

PDB Information

PDB5UOP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman spumaretrovirus
Primary Citation
Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV.
Schreier, J.D., Embrey, M.W., Raheem, I.T., Barbe, G., Campeau, L.C., Dubost, D., McCabe Dunn, J., Grobler, J., Hartingh, T.J., Hazuda, D.J., Klein, D., Miller, M.D., Moore, K.P., Nguyen, N., Pajkovic, N., Powell, D.A., Rada, V., Sanders, J.M., Sisko, J., Steele, T.G., Wai, J., Walji, A., Xu, M., Coleman, P.J.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Dna/Inhibitor
Released2017-02-01
Resolution2.850
CATH Insert Date07 May, 2017

PDB Images (10)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Rejected
D 08 May, 2017 Rejected

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
5uopA01 25 May, 2017 1.10.340.70 Assigned
5uopA02 25 May, 2017 2.30.30.140 Assigned
5uopA03 25 May, 2017 3.30.420.10 Assigned
5uopA04 25 May, 2017 6.10.20.110 Assigned
5uopB00 25 May, 2017 3.30.420.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14350 POL_FOAMV Human spumaretrovirus Pro-Pol polyprotein
P14350 POL_FOAMV Human spumaretrovirus Pro-Pol polyprotein