PDB Information

PDB5UNW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
Cinelli, M.A., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-01-31
Resolution2.040
CATH Insert Date14 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5unwA01 06 Nov, 2017 3.90.340.10 Assigned
5unwA02 06 Nov, 2017 3.90.440.10 Assigned
5unwA03 06 Nov, 2017 3.90.1230.10 Assigned
5unwB01 06 Nov, 2017 3.90.340.10 Assigned
5unwB02 06 Nov, 2017 3.90.440.10 Assigned
5unwB03 06 Nov, 2017 3.90.1230.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain