PDB 5ue4

PDB Information

PDB5UE4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
Scannevin, R.H., Alexander, R., Haarlander, T.M., Burke, S.L., Singer, M., Huo, C., Zhang, Y.M., Maguire, D., Spurlino, J., Deckman, I., Carroll, K.I., Lewandowski, F., Devine, E., Dzordzorme, K., Tounge, B., Milligan, C., Bayoumy, S., Williams, R., Schalk-Hihi, C., Leonard, K., Jackson, P., Todd, M., Kuo, L.C., Rhodes, K.J.
J. Biol. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-12-29
Resolution1.800
CATH Insert Date14 Nov, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ue4A00 10 Dec, 2017 3.40.390.10 Assigned
5ue4B00 10 Dec, 2017 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14780 MMP9_HUMAN Homo sapiens Matrix metalloproteinase-9
P14780 MMP9_HUMAN Homo sapiens Matrix metalloproteinase-9