PDB 5u28

PDB Information

PDB5U28
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.
Andrews, F.H., Singh, A.R., Joshi, S., Smith, C.A., Morales, G.A., Garlich, J.R., Durden, D.L., Kutateladze, T.G.
Proc. Natl. Acad. Sci. U.S.A.
HeaderTranscription Regulator/Inhibitor
Released2016-11-30
Resolution1.800
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5u28A01 23 May, 2017 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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