PDB 5tzh

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Overview

PDB Information

PDB	5TZH
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders. Gomez, L., Massari, M.E., Vickers, T., Freestone, G., Vernier, W., Ly, K., Xu, R., McCarrick, M., Marrone, T., Metz, M., Yan, Y.G., Yoder, Z.W., Lemus, R., Broadbent, N.J., Barido, R., Warren, N., Schmelzer, K., Neul, D., Lee, D., Andersen, C.B., Sebring, K., Aertgeerts, K., Zhou, X., Tabatabaei, A., Peters, M., Breitenbucher, J.G. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-11-21
Resolution	1.600
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5tzh

5tzh

PDB 5tzh

Image of CATH 5tzhA

5tzhA

PDB Chain 5tzhA

Image of CATH 5tzhB

5tzhB

PDB Chain 5tzhB

Image of CATH 5tzhC

5tzhC

PDB Chain 5tzhC

Image of CATH 5tzhD

5tzhD

PDB Chain 5tzhD

Image of CATH 5tzhA00

5tzhA00

CATH Domain 5tzhA00

Image of CATH 5tzhB00

5tzhB00

CATH Domain 5tzhB00

Image of CATH 5tzhC00

5tzhC00

CATH Domain 5tzhC00

Image of CATH 5tzhD00

5tzhD00

CATH Domain 5tzhD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tzhA00	22 May, 2017	1.10.1300.10	Assigned
5tzhB00	22 May, 2017	1.10.1300.10	Assigned
5tzhC00	22 May, 2017	1.10.1300.10	Assigned
5tzhD00	22 May, 2017	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase