PDB 5tyr

PDB Information

PDB5TYR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
Aoki, M., Hayashi, H., Rao, K.V., Das, D., Higashi-Kuwata, N., Bulut, H., Aoki-Ogata, H., Takamatsu, Y., Yedidi, R.S., Davis, D.A., Hattori, S.I., Nishida, N., Hasegawa, K., Takamune, N., Nyalapatla, P.R., Osswald, H.L., Jono, H., Saito, H., Yarchoan, R., Misumi, S., Ghosh, A.K., Mitsuya, H.
Elife
HeaderHydrolase/Hydrolase Inhibitor
Released2016-11-21
Resolution1.800
CATH Insert Date14 Nov, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tyrA00 10 Dec, 2017 2.40.70.10 Assigned
5tyrB00 10 Dec, 2017 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
G0X8E8 G0X8E8_9HIV1 Human immunodeficiency virus 1 Pol protein
G0X8E8 G0X8E8_9HIV1 Human immunodeficiency virus 1 Pol protein