PDB 5tuq

PDB Information

PDB5TUQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 group M subtype B (isolate BH10)
Primary Citation
6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase.
Tang, J., Kirby, K.A., Huber, A.D., Casey, M.C., Ji, J., Wilson, D.J., Sarafianos, S.G., Wang, Z.
Eur J Med Chem
HeaderTransferase/Transferase Inhibitor
Released2016-11-07
Resolution2.710
CATH Insert Date14 Nov, 2017

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
5tuqA01 10 Dec, 2017 3.10.10.10 Assigned
5tuqA02 10 Dec, 2017 3.30.70.270 Assigned
5tuqA03 10 Dec, 2017 3.30.70.270 Assigned
5tuqA04 10 Dec, 2017 3.30.70.270 Assigned
5tuqA05 10 Dec, 2017 3.30.420.10 Assigned
5tuqB01 10 Dec, 2017 3.10.10.10 Assigned
5tuqB02 10 Dec, 2017 3.30.70.270 Assigned
5tuqB03 10 Dec, 2017 3.30.70.270 Assigned
5tuqB04 10 Dec, 2017 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein