PDB 5tqh

PDB Links
Overview

PDB Information

PDB	5TQH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1. Levell, J.R., Caferro, T., Chenail, G., Dix, I., Dooley, J., Firestone, B., Fortin, P.D., Giraldes, J., Gould, T., Growney, J.D., Jones, M.D., Kulathila, R., Lin, F., Liu, G., Mueller, A., van der Plas, S., Slocum, K., Smith, T., Terranova, R., Toure, B.B., Tyagi, V., Wagner, T., Xie, X., Xu, M., Yang, F.S., Zhou, L.X., Pagliarini, R., Cho, Y.S. ACS Med Chem Lett
Header	Oxidoreductase
Released	2016-10-24
Resolution	2.200
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5tqh

5tqh

PDB 5tqh

Image of CATH 5tqhA

5tqhA

PDB Chain 5tqhA

Image of CATH 5tqhB

5tqhB

PDB Chain 5tqhB

Image of CATH 5tqhC

5tqhC

PDB Chain 5tqhC

Image of CATH 5tqhD

5tqhD

PDB Chain 5tqhD

Image of CATH 5tqhA00

5tqhA00

CATH Domain 5tqhA00

Image of CATH 5tqhB00

5tqhB00

CATH Domain 5tqhB00

Image of CATH 5tqhC00

5tqhC00

CATH Domain 5tqhC00

Image of CATH 5tqhD00

5tqhD00

CATH Domain 5tqhD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5tqhA00	22 May, 2017	3.40.718.10	Assigned
5tqhB00	22 May, 2017	3.40.718.10	Assigned
5tqhC00	22 May, 2017	3.40.718.10	Assigned
5tqhD00	22 May, 2017	3.40.718.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic