PDB 5tcc

PDB Information

PDB5TCC
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
Yang, C.Y., Phillips, J.G., Stuckey, J.A., Bai, L., Sun, H., Delproposto, J., Brown, W.C., Chinnaswamy, K.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2016-09-14
Resolution3.370
CATH Insert Date30 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (7)

Chain ID Date inserted into CATH CATH Status
A 31 Oct, 2016 Chopped
B 31 Oct, 2016 Chopped
C 31 Oct, 2016 Chopped
D 31 Oct, 2016 Chopped
E 31 Oct, 2016 Chopped
F 31 Oct, 2016 Chopped
G 31 Oct, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5tccA01 03 Nov, 2016 2.40.10.10 Assigned
5tccA02 03 Nov, 2016 2.40.10.10 Assigned
5tccB01 03 Nov, 2016 2.40.10.10 Assigned
5tccB02 03 Nov, 2016 2.40.10.10 Assigned
5tccC01 03 Nov, 2016 2.40.10.10 Assigned
5tccC02 03 Nov, 2016 2.40.10.10 Assigned
5tccD01 03 Nov, 2016 2.40.10.10 Assigned
5tccD02 03 Nov, 2016 2.40.10.10 Assigned
5tccE01 03 Nov, 2016 2.40.10.10 Assigned
5tccE02 03 Nov, 2016 2.40.10.10 Assigned
5tccF01 03 Nov, 2016 2.40.10.10 Assigned
5tccF02 03 Nov, 2016 2.40.10.10 Assigned
5tccG01 02 Nov, 2016 2.40.10.10 Assigned
5tccG02 02 Nov, 2016 2.40.10.10 Assigned

UniProtKB Entries (7)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
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