PDB 5t97

PDB Information

PDB5T97
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ER alpha + Breast Cancer.
Burks, H.E., Abrams, T., Kirby, C.A., Baird, J., Fekete, A., Hamann, L.G., Kim, S., Lombardo, F., Loo, A., Lubicka, D., Macchi, K., McDonnell, D.P., Mishina, Y., Norris, J.D., Nunez, J., Saran, C., Sun, Y., Thomsen, N.M., Wang, C., Wang, J., Peukert, S.
J. Med. Chem.
HeaderHormone Receptor
Released2016-09-09
Resolution3.000
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5t97A00 21 May, 2017 1.10.565.10 Assigned
5t97B00 21 May, 2017 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor