PDB 5t6g

PDB Information

PDB5T6G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceNorwalk virus
Primary Citation
Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.
Galasiti Kankanamalage, A.C., Kim, Y., Rathnayake, A.D., Damalanka, V.C., Weerawarna, P.M., Doyle, S.T., Alsoudi, A.F., Dissanayake, D.M., Lushington, G.H., Mehzabeen, N., Battaile, K.P., Lovell, S., Chang, K.O., Groutas, W.C.
Eur J Med Chem
HeaderProtease/Protease Inhibitor
Released2016-09-01
Resolution2.450
CATH Insert Date04 Dec, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2016 Chopped
B 05 Dec, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5t6gA01 09 Dec, 2016 2.40.10.10 Assigned
5t6gA02 09 Dec, 2016 2.40.10.10 Assigned
5t6gB01 10 Dec, 2016 2.40.10.10 Assigned
5t6gB02 10 Dec, 2016 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q83883 POLG_NVN68 Norovirus Hu/1968/US Genome polyprotein
Q83883 POLG_NVN68 Norovirus Hu/1968/US Genome polyprotein