PDB 5t35

PDB Information

PDB5T35
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Structural basis of PROTAC cooperative recognition for selective protein degradation.
Gadd, M.S., Testa, A., Lucas, X., Chan, K.H., Chen, W., Lamont, D.J., Zengerle, M., Ciulli, A.
Nat. Chem. Biol.
HeaderLigase
Released2016-08-24
Resolution2.700
CATH Insert Date07 May, 2017

PDB Images (19)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped
E 08 May, 2017 Chopped
F 08 May, 2017 Chopped
G 08 May, 2017 Chopped
H 08 May, 2017 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5t35A00 21 May, 2017 1.20.920.10 Assigned
5t35B00 20 May, 2017 3.10.20.90 Assigned
5t35C00 20 May, 2017 3.30.710.10 Assigned
5t35D01 20 May, 2017 2.60.40.780 Assigned
5t35D02 20 May, 2017 1.10.750.10 Assigned
5t35E00 20 May, 2017 1.20.920.10 Assigned
5t35F00 21 May, 2017 3.10.20.90 Assigned
5t35G00 21 May, 2017 3.30.710.10 Assigned
5t35H01 21 May, 2017 2.60.40.780 Assigned
5t35H02 21 May, 2017 1.10.750.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
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