PDB Information

PDB5SXM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
Alicea-Velazquez, N.L., Shinsky, S.A., Loh, D.M., Lee, J.H., Skalnik, D.G., Cosgrove, M.S.
J.Biol.Chem.
HeaderTranscription
Released2016-08-09
Resolution2.000
CATH Insert Date09 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped
C 10 Oct, 2016 Rejected
D 10 Oct, 2016 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5sxmA00 13 Oct, 2016 2.130.10.10 Assigned
5sxmB00 14 Oct, 2016 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5