PDB 5qtt

PDB Information

PDB5QTT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Potent, Orally Bioavailable and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups.
Corte, J.R., Pinto, D.J.P., Fang, T., Osuna, H., Yang, W., Wang, Y., Lai, A., Clark, C., Sun, J.H., Rampulla, R.A., Mathur, A., Kaspady, M., Neithnadka, P.R., Li, Y.X., Rossi, K.A., Myers, J.E., Sheriff, S., Lou, Z., Harper, T.W., Huang, C.S., Zheng, J.J., Bozarth, J.M., Wu, Y., Wong, P.C., Crain, E., Seiffert, D.A., Luettgen, J.M., Lam, P., Wexler, R.R., Ewing, W.R.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2019-10-16
Resolution2.230
CATH Insert Date29 Dec, 2019

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Chain ID Date inserted into CATH CATH Status

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Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description