PDB 5pzl

PDB Information

PDB5PZL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus genotype 1b (isolate Con1)
Primary Citation
Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.
Yeung, K.S., Beno, B.R., Parcella, K., Bender, J.A., Grant-Young, K.A., Nickel, A., Gunaga, P., Anjanappa, P., Bora, R.O., Selvakumar, K., Rigat, K., Wang, Y.K., Liu, M., Lemm, J., Mosure, K., Sheriff, S., Wan, C., Witmer, M., Kish, K., Hanumegowda, U., Zhuo, X., Shu, Y.Z., Parker, D., Haskell, R., Ng, A., Gao, Q., Colston, E., Raybon, J., Grasela, D.M., Santone, K., Gao, M., Meanwell, N.A., Sinz, M., Soars, M.G., Knipe, J.O., Roberts, S.B., Kadow, J.F.
J. Med. Chem.
HeaderTransferase
Released2017-02-27
Resolution2.060
CATH Insert Date14 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 May, 2017 Chopped
B 15 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5pzlA01 06 Nov, 2017 Holding pen
5pzlA02 06 Nov, 2017 Holding pen
5pzlB01 06 Nov, 2017 Holding pen
5pzlB02 06 Nov, 2017 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein
Q9WMX2 POLG_HCVCO Hepatitis C virus (isolate Con1) Genome polyprotein