PDB 5oew

PDB Information

PDB5OEW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency.
Goffin, E., Drapier, T., Larsen, A.P., Geubelle, P., Ptak, C.P., Laulumaa, S., Rovinskaja, K., Gilissen, J., Tullio, P., Olsen, L., Frydenvang, K., Pirotte, B., Hanson, J., Oswald, R.E., Kastrup, J.S., Francotte, P.
J. Med. Chem.
HeaderMembrane Protein
Released2017-07-10
Resolution2.000
CATH Insert Date03 Jun, 2018

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5oewA01 27 Jun, 2018 3.40.190.10 Assigned
5oewA02 27 Jun, 2018 3.40.190.10 Assigned
5oewB01 27 Jun, 2018 3.40.190.10 Assigned
5oewB02 27 Jun, 2018 3.40.190.10 Assigned
5oewC01 27 Jun, 2018 3.40.190.10 Assigned
5oewC02 27 Jun, 2018 3.40.190.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2