PDB 5ncx

PDB Information

PDB5NCX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceThermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11)
Primary Citation
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase.
Lahav, D., Liu, B., van den Berg, R.J.B.H.N., van den Nieuwendijk, A.M.C.H., Wennekes, T., Ghisaidoobe, A.T., Breen, I., Ferraz, M.J., Kuo, C.L., Wu, L., Geurink, P.P., Ovaa, H., van der Marel, G.A., van der Stelt, M., Boot, R.G., Davies, G.J., Aerts, J.M.F.G., Overkleeft, H.S.
J. Am. Chem. Soc.
HeaderHydrolase
Released2017-03-06
Resolution1.700
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ncxA01 25 Jan, 2018 Holding pen
5ncxA02 25 Jan, 2018 Holding pen

UniProtKB Entries (1)

Accession Gene ID Taxon Description
F6BL85 F6BL85_THEXL Thermoanaerobacterium xylanolyticum LX-11 Glucosylceramidase