PDB 5mu8

PDB Links
Overview

PDB Information

PDB	5MU8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction. Blevitt, J.M., Hack, M.D., Herman, K.L., Jackson, P.F., Krawczuk, P.J., Lebsack, A.D., Liu, A.X., Mirzadegan, T., Nelen, M.I., Patrick, A.N., Steinbacher, S., Milla, M.E., Lumb, K.J. J. Med. Chem.
Header	Cytokine
Released	2017-01-12
Resolution	3.000
CATH Insert Date	07 May, 2017

PDB Images (97)

5mu8

PDB 5mu8

5mu8a

PDB Chain 5mu8a

5mu8A

PDB Chain 5mu8A

5mu8b

PDB Chain 5mu8b

5mu8B

PDB Chain 5mu8B

5mu8c

PDB Chain 5mu8c

5mu8C

PDB Chain 5mu8C

5mu8d

PDB Chain 5mu8d

5mu8D

PDB Chain 5mu8D

5mu8e

PDB Chain 5mu8e

5mu8f

PDB Chain 5mu8f

5mu8F

PDB Chain 5mu8F

5mu8g

PDB Chain 5mu8g

5mu8G

PDB Chain 5mu8G

5mu8h

PDB Chain 5mu8h

5mu8H

PDB Chain 5mu8H

5mu8i

PDB Chain 5mu8i

5mu8I

PDB Chain 5mu8I

5mu8j

PDB Chain 5mu8j

5mu8J

PDB Chain 5mu8J

5mu8k

PDB Chain 5mu8k

5mu8K

PDB Chain 5mu8K

5mu8l

PDB Chain 5mu8l

5mu8L

PDB Chain 5mu8L

5mu8m

PDB Chain 5mu8m

5mu8M

PDB Chain 5mu8M

5mu8n

PDB Chain 5mu8n

5mu8N

PDB Chain 5mu8N

5mu8o

PDB Chain 5mu8o

5mu8O

PDB Chain 5mu8O

5mu8p

PDB Chain 5mu8p

5mu8P

PDB Chain 5mu8P

5mu8q

PDB Chain 5mu8q

5mu8Q

PDB Chain 5mu8Q

5mu8r

PDB Chain 5mu8r

5mu8R

PDB Chain 5mu8R

5mu8s

PDB Chain 5mu8s

5mu8S

PDB Chain 5mu8S

5mu8t

PDB Chain 5mu8t

5mu8T

PDB Chain 5mu8T

5mu8u

PDB Chain 5mu8u

5mu8U

PDB Chain 5mu8U

5mu8v

PDB Chain 5mu8v

5mu8V

PDB Chain 5mu8V

5mu8w

PDB Chain 5mu8w

5mu8W

PDB Chain 5mu8W

5mu8X

PDB Chain 5mu8X

5mu8Y

PDB Chain 5mu8Y

5mu8Z

PDB Chain 5mu8Z

5mu8a00

CATH Domain 5mu8a00

5mu8A00

CATH Domain 5mu8A00

5mu8b00

CATH Domain 5mu8b00

5mu8B00

CATH Domain 5mu8B00

5mu8c00

CATH Domain 5mu8c00

5mu8C00

CATH Domain 5mu8C00

5mu8d00

CATH Domain 5mu8d00

5mu8D00

CATH Domain 5mu8D00

5mu8e00

CATH Domain 5mu8e00

5mu8f00

CATH Domain 5mu8f00

5mu8F00

CATH Domain 5mu8F00

5mu8g00

CATH Domain 5mu8g00

5mu8G00

CATH Domain 5mu8G00

5mu8h00

CATH Domain 5mu8h00

5mu8H00

CATH Domain 5mu8H00

5mu8i00

CATH Domain 5mu8i00

5mu8I00

CATH Domain 5mu8I00

5mu8j00

CATH Domain 5mu8j00

5mu8J00

CATH Domain 5mu8J00

5mu8k00

CATH Domain 5mu8k00

5mu8K00

CATH Domain 5mu8K00

5mu8l00

CATH Domain 5mu8l00

5mu8L00

CATH Domain 5mu8L00

5mu8m00

CATH Domain 5mu8m00

5mu8M00

CATH Domain 5mu8M00

5mu8n00

CATH Domain 5mu8n00

5mu8N00

CATH Domain 5mu8N00

5mu8o00

CATH Domain 5mu8o00

5mu8O00

CATH Domain 5mu8O00

5mu8p00

CATH Domain 5mu8p00

5mu8P00

CATH Domain 5mu8P00

5mu8q00

CATH Domain 5mu8q00

5mu8Q00

CATH Domain 5mu8Q00

5mu8r00

CATH Domain 5mu8r00

5mu8R00

CATH Domain 5mu8R00

5mu8s00

CATH Domain 5mu8s00

5mu8S00

CATH Domain 5mu8S00

5mu8t00

CATH Domain 5mu8t00

5mu8T00

CATH Domain 5mu8T00

5mu8u00

CATH Domain 5mu8u00

5mu8U00

CATH Domain 5mu8U00

5mu8v00

CATH Domain 5mu8v00

5mu8V00

CATH Domain 5mu8V00

5mu8w00

CATH Domain 5mu8w00

5mu8W00

CATH Domain 5mu8W00

5mu8X00

CATH Domain 5mu8X00

5mu8Y00

CATH Domain 5mu8Y00

5mu8Z00

CATH Domain 5mu8Z00

PDB Prints

PDB Chains (48)

Chain ID	Date inserted into CATH	CATH Status
a	08 May, 2017	Chopped
A	08 May, 2017	Chopped
b	08 May, 2017	Chopped
B	08 May, 2017	Chopped
c	08 May, 2017	Chopped
C	08 May, 2017	Chopped
d	08 May, 2017	Chopped
D	08 May, 2017	Chopped
e	08 May, 2017	Chopped
f	08 May, 2017	Chopped
F	08 May, 2017	Chopped
g	08 May, 2017	Chopped
G	08 May, 2017	Chopped
h	08 May, 2017	Chopped
H	08 May, 2017	Chopped
i	08 May, 2017	Chopped
I	08 May, 2017	Chopped
j	08 May, 2017	Chopped
J	08 May, 2017	Chopped
k	08 May, 2017	Chopped
K	08 May, 2017	Chopped
l	08 May, 2017	Chopped
L	08 May, 2017	Chopped
m	08 May, 2017	Chopped
M	08 May, 2017	Chopped
n	08 May, 2017	Chopped
N	08 May, 2017	Chopped
o	08 May, 2017	Chopped
O	08 May, 2017	Chopped
p	08 May, 2017	Chopped
P	08 May, 2017	Chopped
q	08 May, 2017	Chopped
Q	08 May, 2017	Chopped
r	08 May, 2017	Chopped
R	08 May, 2017	Chopped
s	08 May, 2017	Chopped
S	08 May, 2017	Chopped
t	08 May, 2017	Chopped
T	08 May, 2017	Chopped
u	08 May, 2017	Chopped
U	08 May, 2017	Chopped
v	08 May, 2017	Chopped
V	08 May, 2017	Chopped
w	08 May, 2017	Chopped
W	08 May, 2017	Chopped
X	08 May, 2017	Chopped
Y	08 May, 2017	Chopped
Z	08 May, 2017	Chopped

CATH Domains (48)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5mu8a00	17 May, 2017	2.60.120.40	Assigned
5mu8A00	17 May, 2017	2.60.120.40	Assigned
5mu8b00	17 May, 2017	2.60.120.40	Assigned
5mu8B00	17 May, 2017	2.60.120.40	Assigned
5mu8c00	17 May, 2017	2.60.120.40	Assigned
5mu8C00	17 May, 2017	2.60.120.40	Assigned
5mu8d00	17 May, 2017	2.60.120.40	Assigned
5mu8D00	17 May, 2017	2.60.120.40	Assigned
5mu8e00	17 May, 2017	2.60.120.40	Assigned
5mu8f00	17 May, 2017	2.60.120.40	Assigned
5mu8F00	17 May, 2017	2.60.120.40	Assigned
5mu8g00	17 May, 2017	2.60.120.40	Assigned
5mu8G00	17 May, 2017	2.60.120.40	Assigned
5mu8h00	17 May, 2017	2.60.120.40	Assigned
5mu8H00	17 May, 2017	2.60.120.40	Assigned
5mu8i00	17 May, 2017	2.60.120.40	Assigned
5mu8I00	17 May, 2017	2.60.120.40	Assigned
5mu8j00	17 May, 2017	2.60.120.40	Assigned
5mu8J00	17 May, 2017	2.60.120.40	Assigned
5mu8k00	17 May, 2017	2.60.120.40	Assigned
5mu8K00	17 May, 2017	2.60.120.40	Assigned
5mu8l00	17 May, 2017	2.60.120.40	Assigned
5mu8L00	17 May, 2017	2.60.120.40	Assigned
5mu8m00	17 May, 2017	2.60.120.40	Assigned
5mu8M00	17 May, 2017	2.60.120.40	Assigned
5mu8n00	17 May, 2017	2.60.120.40	Assigned
5mu8N00	17 May, 2017	2.60.120.40	Assigned
5mu8o00	17 May, 2017	2.60.120.40	Assigned
5mu8O00	17 May, 2017	2.60.120.40	Assigned
5mu8p00	17 May, 2017	2.60.120.40	Assigned
5mu8P00	17 May, 2017	2.60.120.40	Assigned
5mu8q00	17 May, 2017	2.60.120.40	Assigned
5mu8Q00	17 May, 2017	2.60.120.40	Assigned
5mu8r00	17 May, 2017	2.60.120.40	Assigned
5mu8R00	17 May, 2017	2.60.120.40	Assigned
5mu8s00	17 May, 2017	2.60.120.40	Assigned
5mu8S00	17 May, 2017	2.60.120.40	Assigned
5mu8t00	17 May, 2017	2.60.120.40	Assigned
5mu8T00	17 May, 2017	2.60.120.40	Assigned
5mu8u00	17 May, 2017	2.60.120.40	Assigned
5mu8U00	17 May, 2017	2.60.120.40	Assigned
5mu8v00	17 May, 2017	2.60.120.40	Assigned
5mu8V00	17 May, 2017	2.60.120.40	Assigned
5mu8w00	17 May, 2017	2.60.120.40	Assigned
5mu8W00	17 May, 2017	2.60.120.40	Assigned
5mu8X00	17 May, 2017	2.60.120.40	Assigned
5mu8Y00	17 May, 2017	2.60.120.40	Assigned
5mu8Z00	17 May, 2017	2.60.120.40	Assigned

UniProtKB Entries (48)

Accession	Gene ID	Taxon	Description
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor
P01375	TNFA_HUMAN	Homo sapiens	Tumor necrosis factor