PDB Information

PDB5MTX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, Synthesis, and Biological Evaluation of Novel Type I(1)/2 p38 alpha MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine.
Walter, N.M., Wentsch, H.K., Buhrmann, M., Bauer, S.M., Doring, E., Mayer-Wrangowski, S., Sievers-Engler, A., Willemsen-Seegers, N., Zaman, G., Buijsman, R., Lammerhofer, M., Rauh, D., Laufer, S.A.
J. Med. Chem.
HeaderTransferase
Released2017-01-11
Resolution1.800
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5mtxA01 10 Dec, 2017 3.30.200.20 Assigned
5mtxA02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14