PDB 5m6e

PDB Information

PDB5M6E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP).
Tamanini, E., Buck, I.M., Chessari, G., Chiarparin, E., Day, J.E.H., Frederickson, M., Griffiths-Jones, C.M., Hearn, K., Heightman, T.D., Iqbal, A., Johnson, C.N., Lewis, E.J., Martins, V., Peakman, T., Reader, M., Rich, S.J., Ward, G.A., Williams, P.A., Wilsher, N.E.
J. Med. Chem.
HeaderApoptosis
Released2016-10-25
Resolution2.320
CATH Insert Date14 Nov, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5m6eA00 10 Dec, 2017 1.10.1170.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
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