PDB 5lli
PDB Information
| PDB | 5LLI |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Potent and selective chemical probe of hypoxic signalling downstream of HIF-alpha hydroxylation via VHL inhibition.
Nat Commun
|
| Header | Ligase |
| Released | 2016-07-27 |
| Resolution | 2.400 |
| CATH Insert Date | 20 Nov, 2016 |
PDB Images (29)
5lli
PDB 5lli
5lliA
PDB Chain 5lliA
5lliB
PDB Chain 5lliB
5lliC
PDB Chain 5lliC
5lliD
PDB Chain 5lliD
5lliE
PDB Chain 5lliE
5lliF
PDB Chain 5lliF
5lliG
PDB Chain 5lliG
5lliH
PDB Chain 5lliH
5lliI
PDB Chain 5lliI
5lliJ
PDB Chain 5lliJ
5lliK
PDB Chain 5lliK
5lliL
PDB Chain 5lliL
5lliA00
CATH Domain 5lliA00
5lliB00
CATH Domain 5lliB00
5lliC01
CATH Domain 5lliC01
5lliC02
CATH Domain 5lliC02
5lliD00
CATH Domain 5lliD00
5lliE00
CATH Domain 5lliE00
5lliF01
CATH Domain 5lliF01
5lliF02
CATH Domain 5lliF02
5lliG00
CATH Domain 5lliG00
5lliH00
CATH Domain 5lliH00
5lliI01
CATH Domain 5lliI01
5lliI02
CATH Domain 5lliI02
5lliJ00
CATH Domain 5lliJ00
5lliK00
CATH Domain 5lliK00
5lliL01
CATH Domain 5lliL01
5lliL02
CATH Domain 5lliL02
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 21 Nov, 2016 | Chopped |
| B | 21 Nov, 2016 | Chopped |
| C | 21 Nov, 2016 | Chopped |
| D | 21 Nov, 2016 | Chopped |
| E | 21 Nov, 2016 | Chopped |
| F | 21 Nov, 2016 | Chopped |
| G | 21 Nov, 2016 | Chopped |
| H | 21 Nov, 2016 | Chopped |
| I | 21 Nov, 2016 | Chopped |
| J | 21 Nov, 2016 | Chopped |
| K | 21 Nov, 2016 | Chopped |
| L | 21 Nov, 2016 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5lliA00 | 25 Nov, 2016 | 3.10.20.90 | Assigned |
| 5lliB00 | 25 Nov, 2016 | 3.30.710.10 | Assigned |
| 5lliC01 | 24 Nov, 2016 | 2.60.40.780 | Assigned |
| 5lliC02 | 24 Nov, 2016 | 1.10.750.10 | Assigned |
| 5lliD00 | 25 Nov, 2016 | 3.10.20.90 | Assigned |
| 5lliE00 | 25 Nov, 2016 | 3.30.710.10 | Assigned |
| 5lliF01 | 25 Nov, 2016 | 2.60.40.780 | Assigned |
| 5lliF02 | 25 Nov, 2016 | 1.10.750.10 | Assigned |
| 5lliG00 | 25 Nov, 2016 | 3.10.20.90 | Assigned |
| 5lliH00 | 24 Nov, 2016 | 3.30.710.10 | Assigned |
| 5lliI01 | 25 Nov, 2016 | 2.60.40.780 | Assigned |
| 5lliI02 | 25 Nov, 2016 | 1.10.750.10 | Assigned |
| 5lliJ00 | 24 Nov, 2016 | 3.10.20.90 | Assigned |
| 5lliK00 | 25 Nov, 2016 | 3.30.710.10 | Assigned |
| 5lliL01 | 25 Nov, 2016 | 2.60.40.780 | Assigned |
| 5lliL02 | 25 Nov, 2016 | 1.10.750.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
