PDB Information

Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells.
Jones, S., Ahmet, J., Ayton, K., Ball, M., Cockerill, M., Fairweather, E., Hamilton, N., Harper, P., Hitchin, J., Jordan, A., Levy, C., Lopez, R., McKenzie, E., Packer, M., Plant, D., Simpson, I., Simpson, P., Sinclair, I., Somervaille, T.C., Small, H., Spencer, G.J., Thomson, G., Tonge, M., Waddell, I., Walsh, J., Waszkowycz, B., Wigglesworth, M., Wiseman, D.H., Ogilvie, D.
CATH Insert Date25 Dec, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 Dec, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5l58A00 30 Dec, 2016 3.40.718.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic