PDB Information

PDB5L3B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Pilotto, S., Speranzini, V., Marabelli, C., Rusconi, F., Toffolo, E., Grillo, B., Battaglioli, E., Mattevi, A.
Hum.Mol.Genet.
HeaderOxidoreductase/Repressor
Released2016-04-06
Resolution3.300
CATH Insert Date15 May, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5l3bA01 21 Jul, 2016 1.10.10.10 Assigned
5l3bA02 21 Jul, 2016 Holding pen
5l3bA03 21 Jul, 2016 1.10.287.80 Assigned
5l3bB00 21 Jul, 2016 1.20.58.1880 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60341 KDM1A_HUMAN Homo sapiens Lysine-specific histone demethylase 1A
Q9UKL0 RCOR1_HUMAN Homo sapiens REST corepressor 1